Liver Diseases & Hepatology

Liver Regeneration and Stem Cell Therapy

Liver regeneration is a fascinating process where the liver can repair and replace damaged tissue. It's a highly orchestrated sequence of events involving various cell types and signaling pathways. While the liver has a remarkable ability to regenerate, severe or chronic damage can overwhelm this capacity, leading to liver dysfunction or failure.

Stem cell therapy holds promise as a potential treatment for liver diseases and injuries. Stem cells have the ability to differentiate into various cell types, including liver cells (hepatocytes), making them attractive candidates for regenerating damaged liver tissue. There are several types of stem cells being investigated for liver regeneration, including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and adult stem cells such as mesenchymal stem cells (MSCs) and hepatic progenitor cells. Researchers are exploring different approaches to harness the regenerative potential of stem cells for liver therapy.