Mahreen Ul Hassan
Sheffield University
Title: The retrospective study to find prevalence of Hepatitis-B and Hepatitis-C related liver cirrhosis and prognosis
Biography
Biography: Mahreen Ul Hassan
Abstract
Cirrhosis is a life threatening disease that end up with Hepatocellular carcinoma or end stage liver cancer ,the relationship of HCV, HBV with liver cirrhosis and its contribution in development of HCC To study the prevalence of HBV and HCV among admitted patients in KPK in KTH (Khyber teaching hospital) related to liver cirrhosis and prognosis.
A retrospective study is carried out in which 415 patients are diagnosed from Medical units of different hospitals in Peshawar from April 2012- January 2014.Inclusion criteria was patients with HCV and HBV positive along with liver cirrhosis, both male and female and age group above 15years. . Out of 415, male were 212 and female 203 and patients mostly effected were of age between 16-80 year with mean age of 52. Third generation ELISA protocol was carried out to diagnose Hepatitis-C and Hepatitis-B virus in which male 49.2% and females 39.2% HCV positive followed by HBV positive in male 27.8 % and female 24.7%. Other possible risk factors include Alcohol in 47.1% male and 0 in female , Diabetes 36% male and 20.2% female, Wilson’s disease 0.9% male and 0.5% female and obesity 6.66% and 11.3% in male and female respectively. Complications such as Ascites, Encephalopathy, Hematemasis, Anaemia are more likely to be seen.